FAQ

6 – OXO Can Women take 6-OXO?
No, 6-OXO is not designed for women. It is strongly recommended that women not take 6-OXO.

Will 6-OXO help treat pre-existing gynecomastia?
Gynecomastia is an estrogen dependent benign growth of the breast tissue, so it follows that any substance that controls the formation of estrogen can help minimize the progression and the severity of the disorder. No estrogen inhibiting or blocking supplement or drug can actually get rid of gynecomastia completely once it has formed however. To completely get rid of gynecomastia requires an operation by a plastic surgeon.

What are the effects of 6-OXO on sperm count?
If sperm count is low due to lack of gonadotropins (FSH especially) then it can raise it.

Why should I take 6-OXO at night?
6-OXO should be taken at night because that is when endogenous estrogen production is maximized. An alternate way to take 6-OXO is to split your dosage into morning and nighttime doses. It should always be taken with meals however.

How long should I take 6-OXO?
6-OXO should be taken at least 2 weeks for testosterone production to be stimulated fully. Total cycle length can be anywhere from 2 to 6 weeks if you are taking it to recover from a cycle of prohormones or active hormones. The general rule is, the longer you are on your cycle and the stronger the hormonal product you are taking is, the longer you should take 6-OXO afterwards.

How should I take 6-OXO if I am coming off of a prohormone cycle?
You should start the 6-OXO immediately after completion a hormone cycle. For the first week, take 600mg a day, and then reduce the dose to 400mg a day the next week, followed by 200mg the final week. You may alter the length of time you take the 6-OXO if you wish, depending on how much suppression you feel you have experienced during your cycle, but keep the same general scheme of starting at the high dose and tapering down.

If I am taking 6-OXO on its own as a natural testosterone booster, then how long should I take it for and how much should I take?
6-OXO is often taken as a means to stimulate natural production of testosterone in non-prohormone users. Taken in this regard, longer cycles are recommended. Cycle lengths of 6 to 12 weeks are best. The amount of 6-OXO to be taken daily can vary from 3-6 caps, however during the first 2 weeks of the cycle it is highly recommended that the full 6 caps a day dose be taken.

Is there a rebound increase in estrogen production after taking 6-OXO?
There is no indication that estrogen rebounds significantly after taking 6-OXO. Studies done on similar aromatase inhibitors have shown that hormone levels normalize back to baseline levels, and that no over-compensation occurs.

Can I take 6-OXO along with other prohormones?
Yes, you may use 6-OXO during a prohormone cycle to help control estrogen formation and to help minimize shutdown of the hypothalamic pituitary testicular axis (HPTA). This is especially beneficial if you are taking a prohormone that either aromatizes directly (androstenedione) or can convert to a hormone that aromatizes (4-androstenediol, 19-nor-4-androstenediol). In the case of non aromatizing prohormones like 1-AD, the concomitant use of 6-OXO is not as necessary since estrogen formation is not an issue. For use during a cycle, a daily dose of 300-600mg is recommended.

Have there been any clinical studies done on 6-OXO?
Yes. A recently completed clinical study was done by Thomas Incledon at Human Performance Specialists Inc. The study was done on 7 men with normal endocrinological profiles. 600mg of 6-OXO was administered daily over the course of 3 weeks. At the end of the three weeks, the testosterone levels of the men roughly doubled, while estradiol dropped slightly. Consequently, there was a very large rise in the testosterone / estradiol ratio, which is the most important variable. There was no evidence of liver toxicity, adverse blood lipid changes, or any other safety concerns. The full data is awaiting peer review and publication.

Can Women take 6-OXO Extreme?
No, 6-OXO Extreme is not designed for women. It is strongly recommended that women not take 6-OXO Extreme.

Will 6-OXO Extreme help treat pre-existing gynecomastia?
Gynecomastia is an estrogen dependent benign growth of the breast tissue, so it follows that any substance that controls the formation of estrogen can help minimize the progression and the severity of the disorder. No estrogen inhibiting or blocking supplement or drug can actually get rid of gynecomastia completely once it has formed however. To completely get rid of gynecomastia requires an operation by a plastic surgeon.

What are the effects of 6-OXO Extreme on sperm count?
If sperm count is low due to lack of gonadotropins (FSH especially) then it can raise it.

Why should I take 6-OXO Exteme at night?
6-OXO Extreme should be taken at night because that is when endogenous estrogen production is maximized. An alternate way to take 6-OXO Exteme is to split your dosage into morning and nighttime doses. It should always be taken with meals however.

How should I use 6-OXO Extreme after a cycle?
6-OXO Extreme can be used for either the duration of a PCT or in conjunction with regular 6-OXO™.

A good example of a 6-OXO Extreme only cycle is:

* Week 1 - 6-OXO Extreme 10 caps per day
* Week 2 - 6-OXO Extreme 8 caps per day
* Week 3 - 6-OXO Extreme 5 caps per day
* Week 4 - 6-OXO Extreme 3 caps per day

A combination 6-OXO Extreme & 6-OXO cycle might be:

* Week 1 - 6-OXO Extreme 10 caps per day
* Week 2 - 6-OXO Extreme 5 caps per day & 6-OXO 3 caps per day
* Week 3 - 6-OXO 6 caps per day
* Week 4 - 6-OXO 3 caps per day

11OXO What is 11 OXO?
11 OXO is adrenosterone which is a hormone produced in the adrenal glands under the influence of adrenocorticotropic hormone (ACTH).

How does 11 OXO work?
11 OXO works in two ways. First, it is a prohormone to 11-ketotesterone which is a non-aromatizing analog of testosterone. It shares many of testosterone’s benefits such as increased libido and increased muscle mass.

11 OXO also works by selectively inhibiting the function of the 11beta-hydroxysteroid dehydrogenase type1 reductase (11HSD1R), an enzyme responsible for converting cortisone to cortisol in target tissues such as fat, liver, and muscle. 11 OXO simply occupies the enzyme, preventing cortisone from accessing it. This is known as competitive inhibition. If cortisone cannot access 11HSD1R then it won't have the opportunity to be converted to cortisol at the target tissue. The nice thing about 11 OXO is that it selectively acts on the 11HSD1R enzyme. Thus, 11 OXO offers a method of controlling the negative actions of cortisol on the body without blocking cortisol's vital functions necessary for life.

Is 11 OXO useful only for cutting? What if I’m bulking?
Cutting is its forte, however it is still very good for bulking. 11 OXO will help minimize fat deposition while on a hypercaloric diet.

Is 11 OXO suppressive?
11 OXO may cause suppression at high doses due to the fact that it converts to 11-ketotestosterone, a potent androgen. This is exhibited especially at higher doses, 6+ caps/day. Always make sure to run the proper PCT after each cycle.

Is 11 OXO estrogenic?
11 OXO does not aromatize and it has a very low intrinsic estrogenic potential. In fact, in a study comparing it to 18 other common androgenic steroids it showed the lowest estrogenic potency (as measured through uterotrophic activity).

Do I need liver support while on cycle?
No, 11 OXO is not a methylated androgen and thus does not pose any substantial strain on the liver.

Any rebound in cortisol after use of 11 OXO?
There are no outward signs of cortisol rebound when reasonable dosages are utilized.

How long should I run 11 OXO?
It is suggested that you run 11 OXO no longer than 8 weeks.

Can I stack 11OXO with other prohormones?
11 OXO works quite well on its own however one can stack with other hormonal products. Of course post cycle therapy (PCT) becomes more of a necessity when other hormonal products are utilized.

Do I need PCT after I’m done taking 11 OXO?
In doses under 3 capsules per day it is not required. In doses over 3 capsules a day but under 6 capsules a day it is recommended. In doses over 6 caps a day it is highly recommended.
Refer to Cycle Suggestions

What is 11 OXO’s half life?
11 OXO's pharmacokinetic profile should be similar to non-methyl prohormones. Peak blood levels should be attained in about an hour after ingestion. Then it should start to decline returning to baseline after 4 to 5 hours.

Should I take 11 OXO before bed?
It is suspected that the morning cortisol rise is an important part of arousal so the user may not want to interfere with that by taking it night before. It may not make any difference but if the user had to make a choice then it is recommended that they avoid evening dosing.

Should I take 11 OXO with meals?
It is recommended to take 11 OXO with a meal containing some fat.

Does 11 OXO have any side effects?
Potential side effects with 11 OXO are the same as with all prohormone products. Most common would be acne, acceleration of male pattern baldness (if genetically susceptible), and increased or decreased sex drive. Also, increased appetite has been reported.

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